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Dean Perspectives
Representative Client Engagement – Market Opportunity Assessment
Client Problem:
- Dean & Company was engaged by Diffusion Pharmaceuticals, a private clinical-stage pharmaceutical company, to conduct a market opportunity assessment of two indications for its lead product candidate, trans sodium crocetinate (TSC)
- TSC is a small-molecule drug that enhances oxygen diffusion to oxygen-deprived (hypoxic) tissues. Its potential therapeutic applications include:
- Critical/Acute Care: Trauma, hemorrhage, stroke, heart attack
- Chronic Care: Cardiovascular disease, respiratory disorders, peripheral vascular disease (PAD)
- Oncology: Sensitization of tumors for radiation therapy
- The goal was to determine and articulate the market opportunity of the drug for potential investors by leveraging our familiarity with the investment community from our decade of private equity experience
Approach:
- Profile the diseases
- Analyze the competitive landscapes
- Benchmark the prices of comparable therapies
Results:
- Dean & Company estimated the peak annual U.S. market opportunity for TSC to be $200MM+ for the radio-sensitization indication and over $800MM+ for the PAD indication
- We then used the market opportunity analysis to develop investor presentations to support Diffusion Pharmaceuticals’ financing efforts
- Additionally, Dean & Company helped Diffusion Pharmaceuticals articulate the regulatory, competitive, and commercial challenges facing the drug, and proposed several approaches to address these challenges
Representative Project Output (Used with Permission):